pyrazolo[1,5-a]pyridine-3-carboxylic acid

pyrazolo[1,5-a]pyridine-3-carboxylic acid - Names and Identifiers

Name	pyrazolo[1,5-a]pyridine-3-carboxylic acid
Synonyms	Pyrazolo pyridine-3-carboxylic acid razolo[1,5-a]pyridine-3-carboxylic acid 3-pyrazolo[1,5-a]pyridinecarboxylic acid PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID pyrazolo[1,5-a]pyridine-3-carboxylic acid H-pyrazolo[1,5-a]pyridine-3-carboxylic acid
CAS	16205-46-2
InChI	InChI=1/C8H6N2O2/c11-8(12)6-5-9-10-4-2-1-3-7(6)10/h1-5H,(H,11,12)

pyrazolo[1,5-a]pyridine-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C8H6N2O2
Molar Mass	162.15
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	199 °C
pKa	-0.61±0.41(Predicted)
Storage Condition	2-8°C
Refractive Index	1.676

pyrazolo[1,5-a]pyridine-3-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
HS Code	29333990

pyrazolo[1,5-a]pyridine-3-carboxylic acid - Introduction

pyrazolo[1,5-a]pyridine-3-carboxylic acid is an organic compound with the chemical formula C10H5NO2. The following is a description of its nature, use, preparation and safety information:

1. Nature:
pyrazolo[1,5-a]pyridine-3-carboxylic acid is a white crystalline solid, soluble in common organic solvents such as alcohols and ethers, and practically insoluble in water. It has stable chemical properties and is not easily oxidized or reduced. The melting point of this compound is 240-242°C.

2. Use:
pyrazolo[1,5-a]pyridine-3-carboxylic acid is mainly used as catalyst and ligand in organic synthesis. It can be used as a ligand for metal catalysts for the preparation of organic compounds with specific structures. In addition, it can also be used as a catalytic acid in organic synthesis reactions.

3. Preparation method:
The preparation method of pyrazolo[1,5-a]pyridine-3-carboxylic acid can be realized by various ways. A common method is by substitution of the amine group of the pyrazole ring to give pyrazolo[1,5-a]pyridine, which is oxidized to pyrazolo[1,5-a]pyridine-3-carboxylic acid. The specific preparation method varies depending on the purpose and conditions of the study.

4. Safety Information:
pyrazolo[1,5-a]pyridine-3-carboxylic acid is relatively safe for human health under normal use conditions, but it is still necessary to pay attention to follow laboratory safety procedures. It may be irritating to the eyes and skin, so wear appropriate protective gloves and goggles during operation. In the event of accidental exposure or misuse, seek medical assistance immediately and present the relevant safety data sheet to your doctor.

Last Update：2024-04-10 22:29:15